Journal
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
Volume 164, Issue 1-2, Pages 18-27Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.resp.2008.07.024
Keywords
Neurotransmitter co-localization; In situ hybridization; Peptides; Respiration; Juxtacellular labeling
Categories
Funding
- [HL28785]
- [HL74011]
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Identifying the major ionotropic neurotransmitter in a respiratory neuron is of critical importance in determining how the neuron fits into the respiratory system, whether in producing or modifying respiratory drive and rhythm. There are now several groups of respiratory neurons whose major neurotransmitters have been identified and in some of these cases, more than one transmitter has been identified in particular neurons. This review will describe the physiologically identified neurons in major respiratory areas that have been phenotyped for major ionotropic transmitters as well as those where more than one transmitter has been identified. Although the purpose of the additional transmitter has not been elucidated for any of the respiratory neurons, some examples from other systems will be discussed. (C) 2008 Elsevier B.V. All rights reserved.
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