Journal
RESPIRATORY MEDICINE
Volume 103, Issue 10, Pages 1400-1405Publisher
W B SAUNDERS CO LTD
DOI: 10.1016/j.rmed.2009.04.007
Keywords
High flow nasal canula; Oxygen therapy; Humidification device; Nasal canula
Funding
- Vapotherm, Inc.
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [P20GM103464] Funding Source: NIH RePORTER
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Recently, heater/humidifier devices that use novel methods to condition breathing gases from an external source have been introduced. The addition of sufficient warmth and high levels of humidification to breathing gas has allowed for higher flow rates from nasal cannula devices to be applied to patients (i.e., high flow therapy). This article provides a review of the proposed mechanisms behind the efficacy of high flow therapy via nasal cannula, which include washout of nasopharyngeal. dead space, attenuation of the inspiratory resistance associated with the nasopharynx, improvement in conductance and pulmonary compliance, mild distending pressure and reduction in energy expenditure for gas conditioning. (C) 2009 Elsevier Ltd. All rights reserved.
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