4.5 Article

One-pot, three-component, green procedure for efficient synthesis of allomaltol derivatives

Journal

RESEARCH ON CHEMICAL INTERMEDIATES
Volume 41, Issue 8, Pages 5149-5158

Publisher

SPRINGER
DOI: 10.1007/s11164-014-1618-5

Keywords

MCRs; Allomaltol derivatives; Synthesis; Ionic liquid

Funding

  1. National Natural Science Foundation of China [21104064, 21172188]
  2. Priority Academic Program Development of Jiangsu Higher Education Institutions

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We report an efficient, mild, one-pot, three-component method, catalyzed by Et3N in the ionic liquid [bmim(+)][BF4 (-)], for synthesis of 2-[(aryl)-(3-hydroxy-6-methyl-4-oxo-4H-pyran-2-yl)methyl]indan-1,3-diones from aromatic aldehydes, 1,3-indanedione, and 5-hydroxy-2-methyl-4H-pyran-4-one. The method has the advantages of high yields, mild reaction conditions, convenient operation, and environmental friendliness.

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