Journal
RESEARCH ON CHEMICAL INTERMEDIATES
Volume 41, Issue 1, Pages 299-309Publisher
SPRINGER
DOI: 10.1007/s11164-013-1192-2
Keywords
Ferulic acid derivatives; Antibacterial; Antifungal
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A series of ferulic acid derivatives (1-38) was synthesized and characterized by physicochemical and spectral means. The synthesized compounds were evaluated in vitro for their antimicrobial activity against different Gram-positive and Gram-negative bacterial and fungal strains by the tube dilution method. Results of antimicrobial screening indicated that compound 1 was the most active antimicrobial agent (pMIC(am) = 1.83 mu M/ml).
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