Journal
RESEARCH ON CHEMICAL INTERMEDIATES
Volume 40, Issue 1, Pages 357-369Publisher
SPRINGER
DOI: 10.1007/s11164-012-0968-0
Keywords
HClO4-SiO2; 1,4-Dihydropyridine; Hantzsch reaction; Multicomponent reaction
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Funding
- University Grants Commission, Government of India, New Delhi [40-44/2011(SR)]
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Facile synthesis of some 1,4-dihydropyridine derivatives via Hantzsch reaction of 5,5-dimethyl-1,3-cyclohexanedione (dimedone), 1,3-diphenyl-2-propen-1-one derivatives and ammonium acetate under solvent-free condition in the presence of silica-supported perchloric acid (HClO4-SiO2) is described. The catalyst is easily prepared, stable, reusable and efficient under the reaction conditions.
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