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A facile strategy for the synthesis of highly substituted imidazole using tetrabutyl ammoniumbromide as catalyst

Journal

RESEARCH ON CHEMICAL INTERMEDIATES
Volume 38, Issue 2, Pages 359-365

Publisher

SPRINGER
DOI: 10.1007/s11164-011-0352-5

Keywords

1,2-Diketone; Aldehyde; Amine; Multi-component condensation; Tetrabutyl ammonium bromide; Ammonium acetate/ammonium formate

Funding

  1. Council of Scientific and Industrial Research (CSIR), New Delhi

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A simple and facile strategy for the synthesis of highly substituted imidazoles has been developed by multi-component condensation of 1,2-diketone, aldehyde, amine, and ammonium acetate in presence of tetrabutyl ammonium bromide as catalyst.

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