Journal
RESEARCH IN MICROBIOLOGY
Volume 160, Issue 4, Pages 267-277Publisher
ELSEVIER
DOI: 10.1016/j.resmic.2009.04.002
Keywords
Chaperones; GroE; DnaK; Protein folding
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Funding
- Wellcome Trust
- Royal Society
- Medical Research Council, UK
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A brief summary of the role of DnaK and GroE chaperones in protein folding precedes a discussion of the role of GroE in Escherichia coli. We consider its obligate substrates, the 8 that are both obligate and essential, and the prospects for constructing a mutant that could survive without it. Structural features of GroE-dependent polypeptides are also considered. (C) 2009 Elsevier Masson SAS. All rights reserved.
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