Journal
RESEARCH IN MICROBIOLOGY
Volume 160, Issue 9, Pages 687-695Publisher
ELSEVIER
DOI: 10.1016/j.resmic.2009.09.006
Keywords
Caulobacter; ClpXP; CtrA; Cyclic di-GMP; Protein localization; Proteolysis
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Funding
- Swiss National Science Foundation Fellowship [3100A0-108186]
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Caulobacter crescentus cell cycle progression is implemented by oscillating global transcriptional regulators that establish temporal and spatial control of modular genetic subsystems during the cell cycle. The hierarchy of this regulatory circuit is established through a combination of gene expression control and regulated proteolysis. Recent results highlight the importance of spatial organization for controlled proteolysis in C. crescentus. (C) 2009 Elsevier Masson SAS. All rights reserved.
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