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Biophysical approaches to study the dynamic process of bacterial adhesion

Journal

RESEARCH IN MICROBIOLOGY
Volume 159, Issue 6, Pages 415-422

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.resmic.2008.04.007

Keywords

biofilm formation; bacterial adhesion; adhesion kinetics; quartz crystal microbalance; surface plasmon resonance; adhesive strength; micromanipulation; optical tweezers; atomic force microscopy; inhibition of adhesion

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Funding

  1. the Swedish Society for Medical Research
  2. the Hedlunds Foundation
  3. the Swedish Royal Academy of Sciences
  4. the Adlerbertska Science Foundation
  5. the Lundgren Science Foundation

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Recent applications of biophysical techniques to the study of adhesion and biofilm formation are playing an important role in broadening our understanding of bacterial interactions. While non-invasive methods enable measurement of adhesion kinetics in real time, single-cell approaches provide information about adhesion forces mediated by specific cell surface structures. Promising approaches are presented in this review. (C) 2008 Elsevier Masson SAS. All nights reserved.

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