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Sex Steroid Hormones and Reproductive Disorders: Impact on Women's Health

Journal

REPRODUCTIVE SCIENCES
Volume 18, Issue 8, Pages 702-712

Publisher

SAGE PUBLICATIONS INC
DOI: 10.1177/1933719111405068

Keywords

sex hormones; primary ovarian insufficiency; polycystic ovary syndrome; endometriosis; endometrial diseases; post menopausal syndrome

Funding

  1. MRC [G0600048, G1002033] Funding Source: UKRI
  2. Medical Research Council [G1002033, G0600048] Funding Source: researchfish
  3. Medical Research Council [G0600048, G1002033, G0600048(80179)] Funding Source: Medline

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The role of sex steroid hormones in reproductive function in women is well established. However, in the last two decades it has been shown that receptors for estrogens, progesterone and androgens are expressed in non reproductive tissue /organs (bone, brain, cardiovascular system) playing a role in their function. Therefore, it is critical to evaluate the impact of sex steroid hormones in the pathophysiology of some diseases (osteoporosis, Alzheimer, atherosclerosis). In particular, women with primary ovarian insufficiency, polycystic ovary syndrome, endometriosis and climacteric syndrome may have more health problems and therefore an hormonal treatment may be crucial for these women.

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