Journal
RENAL FAILURE
Volume 32, Issue 4, Pages 523-527Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/08860221003710554
Keywords
Crohn's disease; glomerulonephritis; IgA nephropathy; inflammatory bowel disease; salicylate nephropathy
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A case of immunoglobulin A nephropathy (IgAN) complicating a 10-year history of biopsy-proven Crohn's disease in a 31-year-old man is described. The patient presented with mild proteinuria and impaired renal function in the setting of an exacerbation of Crohn's disease. Renal biopsy showed IgAN. The patient responded to steroid treatment with clinical remission of the bowel disease and improvement of renal function, while proteinuria remained unchanged. IgA glomerulonephritis is rarely associated with Crohn's disease with only a few previously described cases. We briefly review these cases together with an overview of potential pathophysiological connections between these two diseases.
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