4.5 Article

Effects of Aulosira fertilisima against Cisplatin-Induced Nephrotoxicity and Oxidative Stress in Rats

Journal

RENAL FAILURE
Volume 32, Issue 2, Pages 224-233

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.3109/08860220903541143

Keywords

Aulosira fertilisima; antioxidants; cisplatin; nephrotoxicity; renoprotection

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Oxidative stress due to abnormal production of reactive oxygen molecules (ROM) is believed to be involved in the etiology of toxicities of many xenobiotics. Evidence suggested that ROM is involved in the nephrotoxicity of a widely used synthetic anticancer drug cisplatin. The nephroprotective effects of ethanol extract of Aulosira fertilisima Ghose (EEA) was evaluated using cisplatin (5 mg/kg

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