Journal
REGENERATIVE MEDICINE
Volume 9, Issue 4, Pages 535-549Publisher
FUTURE MEDICINE LTD
DOI: 10.2217/RME.14.20
Keywords
additive manufacturing; bone graft; orthopedic surgery; 3D printing
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Funding
- strategic longer and larger grant (sLOLA) from the Biotechnology and Biological Sciences Research Council, UK [BB/G010579/1]
- EU Biodesign (EU FP7)
- Rosetrees Trust
- Institute for Life Sciences, University of Southampton
- Invibio, UK
- BBSRC [BB/G010579/1] Funding Source: UKRI
- Biotechnology and Biological Sciences Research Council [BB/G010579/1] Funding Source: researchfish
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Additive manufacturing (AM) is a broad term encompassing 3D printing and several other varieties of material processing, which involve computer-directed layer-by-layer synthesis of materials. As the popularity of AM increases, so to do expectations of the medical therapies this process may offer. Clinical requirements and limitations of current treatment strategies in bone grafting, spinal arthrodesis, osteochondral injury and treatment of periprosthetic joint infection are discussed. The various approaches to AM are described, and the current state of clinical translation of AM across these orthopedic clinical scenarios is assessed. Finally, we attempt to distinguish between what AM may offer orthopedic surgery from the hype of what has been promised by AM.
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