4.7 Article

Initial assessment of tumor tracking with a gimbaled linac system in clinical circumstances: A patient simulation study

Journal

RADIOTHERAPY AND ONCOLOGY
Volume 106, Issue 2, Pages 236-240

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2012.12.015

Keywords

Tumor tracking; Stereotactic body radiation therapy; Organ motion

Funding

  1. Flemish government through the Hercules foundation
  2. Fonds voor Wetenschappelijk Onderzoek - Vlaanderen [G.0486.06, G.0412.08]
  3. BrainLab AG

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Purpose: To have an initial assessment of the Vero Dynamic Tracking workflow in clinical circumstances and quantify the performance of the tracking system, a simulation study was set up on 5 lung and liver patients. Methods and materials: The preparatory steps of a tumor tracking treatment, based on fiducial markers implanted in the tumor, were executed allowing pursuit of the tumor with the gimbaled linac and monitoring X-rays acquisition, however, without activating the 6 MV beam. Data were acquired on workflow time-efficiency, tracking accuracy and imaging exposure. Results: The average time between the patient entering the treatment room and the first treatment field was about 9 min. The time for building the correlation model was 3.2 min. Tracking errors of 0.55 and 0.95 mm (1 sigma) were observed in PAN/TILT direction and a 2D range of 3.08 mm. A skin dose was determined of 0.08 mGy/image, with a source-to-skin distance of 900 mm and kV exposure of 1 mAs. On average 1.8 mGy/min kV skin dose was observed for 1 Hz monitoring. Conclusion: The Vero tracking solution proved to be fully functional and showed performance comparable with other real-time tracking systems. (C) 2013 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 106 (2013) 236-240

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