Comparing rigid and deformable dose registration for high dose thoracic re-irradiation

For patients with locally-recurrent lung cancer, high dose thoracic re-irradiation can prolong survival. Deformable image registration improves the accuracy with which initial treatments are accounted for compared to rigid image registration. Using deformable image registration will improve correlative toxicity data, and may reduce toxicity for selected patients undergoing re-irradiation. (C) 2013 Elsevier Ireland Ltd. All rights reserved.