4.7 Article

Enhanced intrinsic radiosensitivity after treatment with stereotactic radiosurgery for an acoustic neuroma

Journal

RADIOTHERAPY AND ONCOLOGY
Volume 103, Issue 3, Pages 410-414

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2012.03.011

Keywords

Stereotactic radiosurgery (SRS); Acoustic neuroma; Radiosensitivity; gamma-H2AX

Funding

  1. National Cancer Institute, National Institute of Health, USA

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Enhanced radiosensitivity is an uncommon phenomenon attributable to deficient DNA repair after radiotherapy which can be assessed with the gamma-H2AX assay. Reports of radiosensitivity after stereotactic radiosurgery (SRS) are uncommon. We describe a case where the clinical, radiological and laboratory findings suggest enhanced radiosensitivity after SRS for an acoustic neuroma. (C) 2012 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 103 (2012) 410-414

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