Journal
RADIOTHERAPY AND ONCOLOGY
Volume 89, Issue 2, Pages 222-226Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.radonc.2008.07.018
Keywords
Hypoxia; NHEJ repair; Ku70/80; p53; angiogenesis; Cervical cancer
Funding
- FIS [1035/98, 0855/01]
- Instituto Canario de Investigacion del Cancer (ICIC)
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Hypoxia may inhibits the NHEJ DNA repair through downregulating Ku70/80 expression and combined with an increased angiogenesis and altered p53 expression would be responsible for tumor progression in cervical carcinoma. (c) 2008 Elsevier Ireland Ltd. All rights reserved. Radiotherapy and Oncology 89 (2008) 222-226.
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