Journal
RADIOLOGY
Volume 258, Issue 2, Pages 351-369Publisher
RADIOLOGICAL SOC NORTH AMERICA
DOI: 10.1148/radiol.10081634
Keywords
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Funding
- NCI NIH HHS [L30 CA136262, R01 CA142737, R01 CA149379] Funding Source: Medline
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Image-guided tumor ablation with both thermal and nonthermal sources has received substantial attention for the treatment of many focal malignancies. Increasing interest has been accompanied by continual advances in energy delivery, application technique, and therapeutic combinations with the intent to improve the efficacy and/or specificity of ablative therapies. This review outlines clinical percutaneous tumor ablation technology, detailing the science, devices, techniques, technical obstacles, current trends, and future goals in percutaneous tumor ablation. Methods such as chemical ablation, cryoablation, high-temperature ablation (radiofrequency, microwave, laser, and ultrasound), and irreversible electroporation will be discussed. Advances in technique will also be covered, including combination therapies, tissue property modulation, and the role of computer modeling for treatment optimization. (C) RSNA, 2011
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