Journal
RADIOLOGY
Volume 254, Issue 1, Pages 1-3Publisher
RADIOLOGICAL SOC NORTH AMERICA
DOI: 10.1148/radiol.091669
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The paradoxical relationship between blood oxygen level-dependent (BOLD) magnetic resonance (MR) imaging and breast cancer hypoxia challenges our current understanding of what we believe is happening to erythrocytes in tumors. The ability of air breathing R-2* measurements to reflect tissue hypoxia appears to be tumor type-specific, which should prompt further exploration of this image contrast mechanism in both human and animal tumors.
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