Journal
RADIOLOGIC CLINICS OF NORTH AMERICA
Volume 47, Issue 5, Pages 827-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.rcl.2009.05.003
Keywords
Gadolinium based contrast media; Nephrogenic systemic fibrosis; Epidemiology; Prevalence; Adverse reactions
Ask authors/readers for more resources
Nephrogenic systemic fibrosis (NSF) is a new disease; the first case was diagnosed in 1997. It took 9 years before an association between NSF and gadolinium-based contrast agents (Gd-CAs) was identified. Gadolinium has several advantages for use in relation to enhanced MRI, but it is also a toxic heavy metal. For nearly 20 years, it was believed that Gd-CAs were safe, and they were used liberally. The prevalence of NSF cases varies between the various Gd-CAs, and adequate documentation of NSF cases after exposure to extracellular Gd-CAs remains a problem. All evidence points toward the fact that the real number of patients who have NSF has not been accurately totaled; the disease seems to be underdiagnosed for various reasons.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available