4.2 Article Proceedings Paper

Next generation platforms for high-throughput biodosimetry

Journal

RADIATION PROTECTION DOSIMETRY
Volume 159, Issue 1-4, Pages 105-110

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/rpd/ncu161

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Funding

  1. Center for High-Throughput Minimally Invasive Radiation Biodosimetry from the National Institute of Allergy and Infectious Disease, National Institutes of Health [U19 A1067773]

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Here the general concept of the combined use of plates and tubes in racks compatible with the American National Standards Institute/the Society for Laboratory Automation and Screening microplate formats as the next generation platforms for increasing the throughput of biodosimetry assays was described. These platforms can be used at different stages of biodosimetry assays starting from blood collection into microtubes organised in standardised racks and ending with the cytogenetic analysis of samples in standardised multiwell and multichannel plates. Robotically friendly platforms can be used for different biodosimetry assays in minimally equipped laboratories and on cost-effective automated universal biotech systems.

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