Fabrication and investigation of single track-etched nanopore and its applications

Solid-state nanopores have been widely used as building blocks for nanofluidic devices and circuits from both fundamental and application aspects. In this review, we sketch the recent research progress in our group on the fabrication and application of single nanopores in PET membrane by track-etching method. The asymmetric ion transport properties in the conical nanopore are intensively studied both experimentally and theoretically. Based on the understanding of the particular ion transport behavior on nanoscale, some applications are present, including the pressure-driven streaming current and synthetic nanopore-DNA system. (C) 2009 Elsevier Ltd. All rights reserved.