Journal
QUIMICA NOVA
Volume 34, Issue 3, Pages 408-413Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0100-40422011000300008
Keywords
resveratrol; lipid-based nanocarriers; hydrogels
Categories
Ask authors/readers for more resources
PREPARATION AND CHARACTERIZATION OF RESVERATROL-LOADED LIPID-BASED NANOCARRIERS FOR CUTANEOUS ADMINISTRATION. Solid lipid nanoparticles (SLN), nanoemulsions (NE), and microemulsions (ME) were prepared by the hot solvent diffusion method, using tristearin or castor oil as oily phase, and soy lecithin and Solutol HS 15 as surfactants. Mean particle sizes ranged from 20 to 215 nm and negative zeta potentials were obtained for all nanocarriers. A HPLC method used to determine resveratrol was specific, linear, exact and precise. The entrapment efficiency was high for all formulations. However, resveratrol content was significantly varied among the lipid nanocarriers. Lipid nanocarrier containing hydrogels exhibiting pseudoplastic behavior were obtained after incorporation of hydroxyethylcellulose in the colloidal dispersions.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available