Journal
QUIMICA NOVA
Volume 31, Issue 5, Pages 1170-1179Publisher
SOC BRASILEIRA QUIMICA
DOI: 10.1590/S0100-40422008000500046
Keywords
glutathione; oxidative stress; cancer
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Glutathione (GSH) and related enzymes are pivoted for the normal functioning of several important biological processes. In this review we discuss the biosynthesis and the catalytic cycles of glutathione as well as the major GSH-related enzymes. We also present how glutathione and enzymes are involved in cancer and the chromatographic and non-chromatographic methods used to analyze glutathione and/or its derivatives.
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