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Nitration inhibits fibrillation of human α-synuclein in vitro by formation of soluble oligomers
G Yamin et al.
FEBS LETTERS (2003)
Polycation-induced oligomerization and accelerated fibrillation of human α-synuclein in vitro
J Goers et al.
PROTEIN SCIENCE (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Golgi fragmentation occurs in the cells with prefibrillar α-synuclein aggregates and precedes the formation of fibrillar inclusion
N Gosavi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
α-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils
HA Lashuel et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Dependence of α-synuclein aggregate morphology on solution conditions
W Hoyer et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Dopamine-dependent neurotoxicity of α-synuclein:: A mechanism for selective neurodegeneration in Parkinson disease
J Xu et al.
NATURE MEDICINE (2002)
Methionine oxidation inhibits fibrillation of human α-synuclein in vitro
VN Uversky et al.
FEBS LETTERS (2002)
Vesicle permeabilization by protofibrillar α-synuclein is sensitive to Parkinson's disease-linked mutations and occurs by a pore-like mechanism
MJ Volles et al.
BIOCHEMISTRY (2002)
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from α-synuclein in vitro
JA Cohlberg et al.
BIOCHEMISTRY (2002)
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck et al.
SCIENCE (2002)
Membrane-bound α-synuclein has a high aggregation propensity and the ability to seed the aggregation of the cytosolic form
HJ Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1
M Funayama et al.
ANNALS OF NEUROLOGY (2002)
Effect of familial Parkinson's disease point mutations A30P and A53T on the structural properties, aggregation, and fibrillation of human α-synuclein
J Li et al.
BIOCHEMISTRY (2001)
The protein-labeling reagent FLASH-EDT2 binds not only to CCXXCC motifs but also non-specifically to endogenous cysteine-rich proteins
K Stroffekova et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2001)
Is Congo red an amyloid-specific dye?
R Khurana et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Inducible expression of mutant α-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
Y Tanaka et al.
HUMAN MOLECULAR GENETICS (2001)
A hydrophobic stretch of 12 amino acid residues in the middle of α-synuclein is essential for filament assembly
BI Giasson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons
PJ McLean et al.
NEUROSCIENCE (2001)
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson et al.
SCIENCE (2000)
Widespread nitration of pathological inclusions in neurodegenerative synucleinopathies
JE Duda et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Fiber diffraction of synthetic α-synuclein filaments shows amyloid-like cross-β conformation
LC Serpell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Fibrils formed in vitro from α-synuclein and two mutant forms linked to Parkinson's disease are typical amyloid
KA Conway et al.
BIOCHEMISTRY (2000)
Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich et al.
NEURON (2000)