4.4 Review

Structure and function of eukaryotic fatty acid synthases

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

Imperfect pseudo-merohedral twinning in crystals of fungal fatty acid synthase

Simon Jenni et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2009)

Article Biochemistry & Molecular Biology

Structure-Function Analysis of the Acyl Carrier Protein Synthase (AcpS) from Mycobacterium tuberculosis

Orly Dym et al.

JOURNAL OF MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Conformational flexibility of metazoan fatty acid synthase enables catalysis

Edward J. Brignole et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Multimeric Options for the Auto-Activation of the Saccharomyces cerevisiae FAS Type I Megasynthase

Patrik Johansson et al.

STRUCTURE (2009)

Article Biochemistry & Molecular Biology

Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases

Jason M. Crawford et al.

CHEMBIOCHEM (2008)

Article Multidisciplinary Sciences

Inhibition of the fungal fatty acid synthase type I multienzyme complex

Patrik Johansson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Multidisciplinary Sciences

The crystal structure of a mammalian fatty acid synthase

Timm Maier et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

A mammalian type I fatty acid synthase acyl carrier protein domain does not sequester acyl chains

Eliza Ploskon et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Chemistry, Multidisciplinary

A short history of SHELX

George M. Sheldrick

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES (2008)

Article Biochemical Research Methods

From electron microscopy to X-ray crystallography: molecular-replacement case studies

Yong Xiong

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Mechanism and substrate recognition of human holo ACP synthase

Gabor Bunkoczi et al.

CHEMISTRY & BIOLOGY (2007)

Review Biochemistry & Molecular Biology

Strategies for crystallization and structure determination of very large macromolecular assemblies

Marcus Mueller et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase

Yinyan Tang et al.

CHEMISTRY & BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat

Charles W. Pemble et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)

Article Biochemical Research Methods

Cryogenic (<20 K) helium cooling mitigates radiation damage to protein crystals

Unmesh Chinte et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2007)

Article Biochemical Research Methods

Reduction of X-ray-induced radiation damage of macromolecular crystals by data collection at 15 K: a systematic study

A. Meents et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2007)

Review Biochemistry & Molecular Biology

The type I fatty acid and polyketide synthases: a tale of two megasynthases

Stuart Smith et al.

NATURAL PRODUCT REPORTS (2007)

Article Biochemistry & Molecular Biology

Structure of acyl carrier protein bound to FabI, the FASII enoyl reductase from Escherichia coli

Salma Rafi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Multidisciplinary Sciences

The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase

Yinyan Tang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Biochemistry & Molecular Biology

Crystal structure of 2-nitropropane dioxygenase complexed with FMN and substrate - Identification of the catalytic base

Jun Yong Ha et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemical Research Methods

Mapping the active site of Escherichia coli malonyl-CoA-acyl carrier protein transacylase (FabD) by protein crystallography

Christian Oefner et al.

ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2006)

Article Biochemistry & Molecular Biology

Solution structures of spinach acyl carrier protein with decanoate and stearate

GA Zornetzer et al.

BIOCHEMISTRY (2006)

Article Multidisciplinary Sciences

Architecture of a fungal fatty acid synthase at 5 Å resolution

S Jenni et al.

SCIENCE (2006)

Article Multidisciplinary Sciences

Architecture of mammalian fatty acid synthase at 4.5 Å resolution

T Maier et al.

SCIENCE (2006)

Article Chemistry, Multidisciplinary

Use of polynuclear metal clusters in protein crystallography

Z Dauter

COMPTES RENDUS CHIMIE (2005)

Article Biochemistry & Molecular Biology

Structure and molecular organization of mammalian fatty acid synthase

FJ Asturias et al.

NATURE STRUCTURAL & MOLECULAR BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Crystal structure of 2-enoyl-CoA hydratase 2 from human peroxisomal multifunctional enzyme type 2

MK Koski et al.

JOURNAL OF MOLECULAR BIOLOGY (2005)

Review Microbiology

Microbial type I fatty acid synthases (FAS): Major players in a network of cellular FAS systems

E Schweizer et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2004)

Article Biochemistry & Molecular Biology

The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa

MS Kimber et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Head-to-head coiled arrangement of the subunits of the animal fatty acid synthase

A Witkowski et al.

CHEMISTRY & BIOLOGY (2004)

Article Multidisciplinary Sciences

Human fatty acid synthase: Structure and substrate selectivity of the thioesterase domain

B Chakravarty et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Biochemistry & Molecular Biology

A two-domain structure of one subunit explains unique features of eukaryotic hydratase 2

MK Koski et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2004)

Article Biochemistry & Molecular Biology

Structure and function of animal fatty acid synthase

SS Chirala et al.

LIPIDS (2004)

Article Biochemistry & Molecular Biology

Key residues responsible for acyl carrier protein and β-ketoacyl-acyl carrier protein reductase (FabG) interaction

YM Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2003)

Review Biochemistry & Molecular Biology

Structural and functional organization of the animal fatty acid synthase

S Smith et al.

PROGRESS IN LIPID RESEARCH (2003)

Article Biochemistry & Molecular Biology

Coenzyme-based functional assignments of short-chain dehydrogenases/reductases (SDRs)

B Persson et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2003)

Article Biochemistry & Molecular Biology

Engineering of an active animal fatty acid synthase dimer with only one competent subunit

AK Joshi et al.

CHEMISTRY & BIOLOGY (2003)

Article Biochemistry & Molecular Biology

SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase fold

JL Martin et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2002)

Article Chemistry, Multidisciplinary

Generic representation and evaluation of properties as a function of position in reciprocal space

K Cowtan

JOURNAL OF APPLIED CRYSTALLOGRAPHY (2002)

Article Biochemistry & Molecular Biology

Medium-chain dehydrogenases/reductases (MDR) -: Family characterizations including genome comparisons and active site modelling

E Nordling et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2002)

Review Biochemistry & Molecular Biology

Forty years of bacterial fatty acid synthesis

CO Rock et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2002)

Article Multidisciplinary Sciences

Quaternary structure of human fatty acid synthase by electron cryomicroscopy

J Brink et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)

Article Biochemical Research Methods

Expression, purification, crystallization and preliminary X-ray analysis of the acyl carrier protein synthase (acpS) from Mycobacterium tuberculosis

S Chopra et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2002)

Article Biochemistry & Molecular Biology

Identification and analysis of the acyl carrier protein (ACP) docking site on β-ketoacyl-ACP synthase III

YM Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)

Article Multidisciplinary Sciences

Human fatty acid synthase: Role of interdomain in the formation of catalytically active synthase dimer

SS Chirala et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Article Biochemistry & Molecular Biology

A novel function of yeast fatty acid synthase -: Subunit α is capable of self-pantetheinylation

F Fichtlscherer et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)