4.6 Review

Cellular orchestrators of renal fibrosis

Journal

QJM-AN INTERNATIONAL JOURNAL OF MEDICINE
Volume 105, Issue 7, Pages 611-615

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/qjmed/hcr235

Keywords

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Funding

  1. MRC [G0501900, G0700330, G0801235]
  2. British Heart Foundation
  3. Kidney Research UK
  4. Genzyme Research Innovation Program
  5. MRC [G0501900, G0801235, G0700330] Funding Source: UKRI
  6. Medical Research Council [G0501900, G0801235, G0700330] Funding Source: researchfish

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Renal fibrosis is a key determinant of the progression of many renal diseases and represents a final common pathway that adversely affects outcome. The evolution of renal fibrosis is complicated and involves many cellular and molecular mediators. In this review we will outline the key players in the fibrotic response of the injured kidney and discuss emerging research in the field.

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