4.3 Article Proceedings Paper

Progress toward red and near-infrared (NIR) emitting saccharide sensors

Journal

PURE AND APPLIED CHEMISTRY
Volume 84, Issue 11, Pages 2443-2456

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1351/PAC-CON-11-11-06

Keywords

boronic acids; fluorescent indicators; naphthorhodamines; near infrared; semi-naphthorhodamines; sugar sensing; xanthenes

Funding

  1. NIH [RO1 EB002044]

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Red-shifted and near-infrared (NIR)-active rhodamine analogs and their boronic acid derivatives were synthesized and studied. These latter compounds function as fluorogenic NIR active substrates for sugar sensing. The effects of benzannulation and boronic acid functionalization on fluorophore optical and sensing properties are described.

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