Journal
PURE AND APPLIED CHEMISTRY
Volume 82, Issue 9, Pages 1797-1812Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1351/PAC-CON-09-09-28
Keywords
annulations; donor-acceptor cyclopropanes; heterocycles; intramolecular; pyrazolidine; pyrrolidine; tetrahydro-oxazine
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Funding
- Natural Sciences and Engineering Research Council of Canada
- Merck Frosst
- American Chemical Society
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The intramolecular reaction of donor-acceptor cyclopropanes with various dipoles and dipolar equivalents allows access to a variety of bicyclic adducts with good stereocontrol. The linkers can often be cleaved to provide stereodefined products.
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