Journal
PSYCHOSOMATICS
Volume 50, Issue 3, Pages 248-254Publisher
ELSEVIER SCIENCE INC
DOI: 10.1176/appi.psy.50.3.248
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Funding
- Alzheimer's Association [IIRG-08-88737]
- National Institute on Aging [R03AG025262, R01AG17649, R01AG030618, K24AG00949]
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Background: Delirium is an acute confusional state that is common, preventable, and life-threatening. Objective: The authors investigated the phenomenology of delirium severity as measured with the Memorial Delirium Assessment Scale among 441 older patients (age 65 and older) admitted with delirium in post-acute care. Methods: Using latent class analysis, they identified four classes of psychomotor-severity subtypes of delirium: 1) hypoactive/mild; 2) hypoactive/severe; 3) mixed, with hyperactive features/severe; and 4) normal/mild. Results: Among those with dementia (N = 166), the hypoactive/mild class was associated with a higher risk of mortality. Among those without dementia (N = 275), greater severity was associated with mortality, regardless of psychomotor features, when compared with the normal/mild class. Conclusion: The data suggest that instruments measuring delirium severity and psychomotor features provide important prognostic information and should be integrated into the assessment of delirium. (Psychosomatics 2009; 50: 248-254)
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