Journal
PSYCHIATRY RESEARCH
Volume 215, Issue 2, Pages 286-293Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2013.11.013
Keywords
Intertemporal; Executive function; Decision making
Categories
Funding
- National Institute of Mental Health [R01 MH81014]
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To study impaired goal-oriented behavior in schizophrenia (SZ), we used a delay discounting task, which consists of a series of choices between receiving a small immediate or larger delayed reward. Few studies of delay discounting have evaluated response consistency (R-2), which is especially relevant in SZ because of documented inconsistency in task performance. We calculated the rate of discounting (k) and R-2 in SZ (n=35) and healthy controls (HC; n=21). Using a criterion value of R-2 > 0.60 to define consistent performance allowed us to compare discounting in consistent SZ and HC, as well as in inconsistent SZ. Groups did not differ significantly in smoking. Compared to HC, consistent SZ showed greater delay. discounting. Both groups exhibited similar patterns of decreasing immediate choices across trial categories, although the decrease was less for SZ. Separate analyses on smokers and non-smokers showed that this group difference was carried by the non-smokers. Inconsistent SZ discounted more than HC and consistent SZ, but their aberrant pattern of choices casts doubt on the validity of their calculated k values. (C) 2013 Elsevier Ireland Ltd. All rights reserved.
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