Journal
PSYCHIATRY RESEARCH
Volume 157, Issue 1-3, Pages 259-263Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.psychres.2007.05.001
Keywords
schizophrenia; medication adherence; electronic monitoring
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Funding
- NIMH NIH HHS [5 K23 MH064930] Funding Source: Medline
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This study examined the reliability and predictive validity of electronic monitoring (EM) in assessing the oral antipsychotic medication adherence of outpatients with schizophrenia or schizoaffective disorder. Sixty-one adult outpatients with schizophrenia or schizoaffective disorder who took a single oral antipsychotic medication were assessed monthly over a 6-month study period with EM of medication bottle opening. Symptom severity, as measured by the Positive and Negative Syndrome Scale (PANSS) total score, was assessed monthly over the 6-month study period. Cronbach's coefficient alpha revealed very high internal reliability (alpha = 0.94). A high degree of test-retest reliability was found (beta ranged from 0.75 to 1.19 and r ranged from 0.63 to 0.90). As for predictive validity, greater mean EM adherence was significantly related to lower mean symptom severity. (c) 2007 Elsevier Ireland Ltd. All rights reserved.
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