Journal
PROTEOMICS CLINICAL APPLICATIONS
Volume 6, Issue 11-12, Pages 548-562Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/prca.201200041
Keywords
Biomarker; Cancer; Pathogen-host interactions; Protein microarray; Serum profiling
Funding
- NIH [RR020839, DK082840, RO1GM076102, CA125807, CA160036, HG006434, R01EY017589]
- NIH (AHA Pre-doctoral Fellowship) [10PRE3040000]
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Functional protein microarrays were developed as a high-throughput tool to overcome the limitations of DNA microarrays and to provide a versatile platform for protein functional analyses. Recent years have witnessed tremendous growth in the use of protein microarrays, particularly functional protein microarrays, to address important questions in the field of clinical proteomics. In this review, we will summarize some of the most innovative and exciting recent applications of protein microarrays in clinical proteomics, including biomarker identification, pathogenhost interactions, and cancer biology.
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