Journal
PROTEOMICS
Volume 14, Issue 20, Pages 2280-2285Publisher
WILEY
DOI: 10.1002/pmic.201300361
Keywords
Bioinformatics; Isobaric tags; Mass spectrometry; Protein quantification; Technology
Funding
- 973 Program of China [2010CB912703]
- Nature Science Foundation of China [91131009]
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Quantitative proteomics technology based on isobaric tags is playing an important role in proteomic investigation. In this paper, we present an automated software, named IQuant, which integrates a postprocessing tool of protein identification and advanced statistical algorithms to process the MS/MS signals generated from the peptides labeled by isobaric tags and aims at proteomics quantification. The software of IQuant, which is freely downloaded at http://sourceforge. net/projects/iquant/, can run from a graphical user interface and a command-line interface, and can work on both Windows and Linux systems.
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