Journal
PROTEOMICS
Volume 11, Issue 6, Pages 1026-1030Publisher
WILEY-BLACKWELL
DOI: 10.1002/pmic.201000578
Keywords
LC-MS/MS; Quality control; Systems Biology
Funding
- Austrian Proteomics Platform (APP) within the Austrian Genome Research Program (GENAU)
- Institute for Molecular Pathology (IMP)
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In the last 15 years, MS-based protein characterization has expanded at a rapid rate. This success is built upon constantly improving instrumentation and a variety of ingenious methods applied to numerous biological questions. However, the reproducibility of mass spectrometric results is considered by many as insufficient. In part, inadequate quality control might be responsible for the lack of reproducibility. Quality control is rarely discussed in scientific publications. Here, we briefly present measures undertaken in our laboratory to foster a general discussion of the subject.
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