Related references
Note: Only part of the references are listed.Coupling of Retinal, Protein, and Water Dynamics in Squid Rhodopsin
Eduardo Jardon-Valadez et al.
BIOPHYSICAL JOURNAL (2010)
Concerted Interconversion between Ionic Lock Substates of the β2 Adrenergic Receptor Revealed by Microsecond Timescale Molecular Dynamics
Tod D. Romo et al.
BIOPHYSICAL JOURNAL (2010)
A Lipid Pathway for Ligand Binding Is Necessary for a Cannabinoid G Protein-coupled Receptor
Dow P. Hurst et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
HIV-1 TAR RNA Spontaneously Undergoes Relevant Apo-to-Holo Conformational Transitions in Molecular Dynamics and Constrained Geometrical Simulations
Simone Fulle et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2010)
Ensemble Docking from Homology Models
Eva Maria Novoa et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2010)
Activation of the Ghrelin Receptor is Described by a Privileged Collective Motion: A Model for Constitutive and Agonist-induced Activation of a Sub-class A G-Protein Coupled Receptor (GPCR)
Nicolas Floquet et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Computational Mapping of the Conformational Transitions in Agonist Selective Pathways of a G-Protein Coupled Receptor
Supriyo Bhattacharya et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2010)
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
Michael P. Bokoch et al.
NATURE (2010)
Importance of the Peptide Backbone Description in Modeling the Selectivity Filter in Potassium Channels
Turgut Bastug et al.
BIOPHYSICAL JOURNAL (2009)
Dynamics of the Internal Water Molecules in Squid Rhodopsin
Eduardo Jardon-Valadez et al.
BIOPHYSICAL JOURNAL (2009)
Analysis of full and partial agonists binding to β2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes
Vsevolod Katritch et al.
JOURNAL OF MOLECULAR RECOGNITION (2009)
Helix movement is coupled to displacement of the second extracellular loop in rhodopsin activation
Shivani Ahuja et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Ligand binding and micro-switches in 7TM receptor structures
Rie Nygaard et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
Ligand-specific changes in M3 muscarinic acetylcholine receptor structure detected by a disulfide scanning strategy
Jian Hua Li et al.
BIOCHEMISTRY (2008)
Flexible ligand docking to multiple receptor conformations: a practical alternative
Maxim Totrov et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2008)
An intracellular loop (IL2) residue confers different basal constitutive activities to the human lutropin receptor and human thyrotropin receptor through structural communication between IL2 and helix 6, via helix 3
Xiuyan Feng et al.
ENDOCRINOLOGY (2008)
Internal hydration increases during activation of the G-protein-coupled receptor rhodopsin
Alan Grossfield et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
Atomistic insights into rhodopsin activation from a dynamic model
Irina G. Tikhonova et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Mechanisms of inter- and intramolecular communication in GPCRs and g proteins
Francesco Raimondi et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2008)
Structure of a β1-adrenergic G-protein-coupled receptor
Tony Warne et al.
NATURE (2008)
Crystal structure of opsin in its G-protein-interacting conformation
Patrick Scheerer et al.
NATURE (2008)
Crystal structure of the ligand-free G-protein-coupled receptor opsin
Jung Hee Park et al.
NATURE (2008)
Structural diversity of G protein-coupled receptors and significance for drug discovery
Malin C. Lagerstrom et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation
Christian Altenbach et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist
Veli-Pekka Jaakola et al.
SCIENCE (2008)
A specific cholesterol binding site is established by the 2.8 Å structure of the human β2-adrenergic receptor
Michael A. Hanson et al.
STRUCTURE (2008)
Conformational changes involved in G-protein-coupled-receptor activation
Juergen Wess et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Sequence of late molecular events in the activation of rhodopsin
Bernhard Knierim et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
High-resolution crystal structure of an engineered human β2-adrenergic G protein-coupled receptor
Vadim Cherezov et al.
SCIENCE (2007)
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
Soren G. F. Rasmussen et al.
NATURE (2007)
Distinct structural changes in a g protein-coupled receptor caused by different classes of agonist ligands
Jian Hua Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Prediction of the 3D structure and dynamics of human DP G-protein coupled receptor bound to an agonist and an antagonist
Youyong Li et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
Intrinsic differences in the response of the human lutropin receptor versus the human follitropin receptor to activating mutations
Meilin Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
G protein-coupled receptors self-assemble in dynamics simulations of model bilayers
Xavier Periole et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2007)
The discovery of long acting β2-adrenoreceptor agonists
Alan D. Brown et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Bio3d: an R package for the comparative analysis of protein structures
Barry J. Grant et al.
BIOINFORMATICS (2006)
A critical assessment of docking programs and scoring functions
Gregory L. Warren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2006)
Modeling activated states of GPCRs: the rhodopsin template
Masha Y. Niv et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2006)
Inactive and active states and supramolecular organization of GPCRs: insights from computational modeling
Francesca Fanelli et al.
JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN (2006)
Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation
Christian E. Elling et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Location of Trp265 in metarhodopsin II: Implications for the activation mechanism of the visual receptor rhodopsin
E Crocker et al.
JOURNAL OF MOLECULAR BIOLOGY (2006)
Essential dynamics:: A tool for efficient trajectory compression and management
T Meyer et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2006)
Importance of the CMAP correction to the CHARMM22 protein force field: Dynamics of hen lysozyme
M Buck et al.
BIOPHYSICAL JOURNAL (2006)
Use of an in situ disulfide cross-linking strategy to study the dynamic properties of the cytoplasmic end of transmembrane domain VI of the M3 muscarinic acetylcholine receptor
SDC Ward et al.
BIOCHEMISTRY (2006)
Identification of an agonist-induced conformational change occurring adjacent to the ligand-binding pocket of the M3 muscarinic acetylcholine receptor
SJ Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Long dynamics simulations of proteins using atomistic force fields and a continuum representation of solvent effects: Calculation of structural and dynamic properties
XF Li et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2005)
Pronounced conformational changes following agonist activation of the M3 muscarinic acetylcholine receptor
SJ Han et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Unveiling the full potential of flexible receptor docking using multiple crystallographic structures
X Barril et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Changes in interhelical hydrogen bonding upon rhodopsin activation
AB Patel et al.
JOURNAL OF MOLECULAR BIOLOGY (2005)
Glide: A new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy
RA Friesner et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Glide: A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening
TA Halgren et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Electron crystallography reveals the structure of metarhodopsin I
JJ Ruprecht et al.
EMBO JOURNAL (2004)
The retinal conformation and its environment in rhodopsin in light of a new 2.2 Å crystal structure
T Okada et al.
JOURNAL OF MOLECULAR BIOLOGY (2004)
Toward the active conformations of rhodopsin and the β2-adrenergic receptor
PR Gouldson et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Domain swapping in the human histamine H1 receptor
RA Bakker et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation
O Fritze et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
An implicit membrane generalized born theory for the study of structure, stability, and interactions of membrane proteins
W Im et al.
BIOPHYSICAL JOURNAL (2003)
β2 adrenergic receptor activation -: Modulation of the proline kink in transmembrane 6 by a rotamer toggle switch
S Lei et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Conserved helix 7 tyrosine acts as a multistate conformational switch in the 5HT2C receptor - Identification of a novel locked-on phenotype and double revertant mutations
C Prioleau et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Seven-transmembrane receptors
KL Pierce et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2002)
Use of an in situ disulfide cross-linking strategy to map proximities between amino acid residues in transmembrane domains I and VII of the M3 muscarinic acetylcholine receptor
FF Hamdan et al.
BIOCHEMISTRY (2002)
Conformational changes that occur during M3 muscarinic acetylcholine receptor activation probed by the use of an in situ disulfide cross-linking strategy
SDC Ward et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Structure and function in rhodopsin: Mapping light-dependent changes in distance between residue 65 in helix TM1 and residues in the sequence 306-319 at the cytoplasmic end of helix TM7 and in helix H8
C Altenbach et al.
BIOCHEMISTRY (2001)
Structure and function in rhodopsin: Mapping light-dependent changes in distance between residue 316 in helix 8 and residues in the sequence 60-75, covering the cytoplasmic end of helices TM1 and TM2 and their connection loop CL1
C Altenbach et al.
BIOCHEMISTRY (2001)
Dimerization of G-protein-coupled receptors
MK Dean et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Conformations of the active and inactive states of opsin
R Vogel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of the β2-adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6
JA Ballesteros et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Activation of rhodopsin: new insights from structural and biochemical studies
T Okada et al.
TRENDS IN BIOCHEMICAL SCIENCES (2001)
The forgotten serine -: A critical role for Ser-2035.42 in ligand binding to and activation of the β2-adrenergic receptor
G Liapakis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Crystal structure of rhodopsin: A G protein-coupled receptor
K Palczewski et al.
SCIENCE (2000)