Journal
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
Volume 78, Issue 15, Pages 3067-3072Publisher
WILEY
DOI: 10.1002/prot.22774
Keywords
protein-protein interaction; protein docking; blind prediction; community-wide experiment
Categories
Funding
- European Union
- French Ministry of Foreign Affairs
- Region Ile-de-France
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Seven rounds of CAPRI predictions with a total of 14 targets were held in the period June 2007 November 2009. In addition to protease/inhibitor complexes and complexes with G-proteins, some of the targets displayed novel features presenting new challenges to the predictors: a complex with RNA, a leucine zipper to be built ab initio, and a human-designed protein. Nine targets were unbound or required model building; the other five had a bound component. Thirteen were assessed, and the results show that the predictor and scorer groups submitted two- or three-star (medium or high quality) models for eight of them, one-star (acceptable) models for three but failed on the unbound RNA complex and another unbound target. Proteins 2010; 78:3067-3072. (C) 2010 Wiley-Liss, Inc.
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