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Implication of Aberrant Glycosylation in Cancer and Use of Lectin for Cancer Biomarker Discovery

Journal

PROTEIN AND PEPTIDE LETTERS
Volume 16, Issue 5, Pages 499-507

Publisher

BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/092986609788167798

Keywords

Aberrant glycosylation; biomarker; cancer; lectin; glycosyltransferase

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Aberrant glycosylation is frequently found in cancer, and efforts for biomarker discovery include the preparation of aberrant glycoproteins as promising analytes. Several lectins that bind to aberrant glycans and can be thus used to capture and enrich aberrant glycoproteins in the frontal stage during biomarker discovery are to be introduced.

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