Journal
ACS COMBINATORIAL SCIENCE
Volume 18, Issue 1, Pages 65-69Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscombsci.5b00145
Keywords
benzimidazoisoquinoline; multicomponent reactions (MCRs); benzimidazole; nucleophilic substitution reaction; one-pot
Funding
- Scientific Research Foundation of Chongqing University of Arts and Sciences [R2013XY01, R2013XY02]
- Chongqing Science and Technology Commission [CSTC2013JCYJA50028]
- National Natural Science Foundations of China [81272598]
- SRF for ROCS, SEM
- Key Laboratory of Tumor Immunopathology, Ministry of Education of China [2013jsz102, 2015SZ0187]
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Two series of benzimidazoisoquinoline and fused benzimidazoisoquinoline-benzimidazole derivatives have been synthesized using an efficient one-pot procedure. This process involves an intramolecular nucleophilic substitution reaction and provides facile access to two series of complexes and potentially interesting biologically active scaffolds.
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