Journal
ACS CATALYSIS
Volume 5, Issue 5, Pages 2846-2849Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.5b00306
Keywords
C-H bond fluorination; phenols; catalysis; nicotinates; late-stage fluorination
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Funding
- National Nature Science Foundation of China [21361130021]
- China Postdoctoral Science Foundation [2014M560494]
- Postdoctoral Science Foundation of Zhejiang Province
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A facile and site-selective C-H bond fluorination of phenols using removable 2-pyridyloxy group as an auxiliary was developed. Alternatively, late-stage C-H bond fluorination of bioactive 2-phenoxyl nicotinate derivatives and diflufenican were also feasible under the present strategy.
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