Journal
PROGRESS IN POLYMER SCIENCE
Volume 37, Issue 2, Pages 211-236Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.progpolymsci.2011.07.008
Keywords
Cyclic carbonate; Functional aliphatic polycarbonate; Ring-opening polymerization; Biomedical application
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Funding
- National Natural Science Foundation of China [20874075]
- Ministry of Science and Technology of China [2011CB606202, 2009CB930300]
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Aliphatic polycarbonates are one important kind of biodegradable polymers and have been commonly used as integral components of engineered tissues, medical devices and drug delivery systems. As far as the biomedical application is concerned, traditional aliphatic polycarbonates usually suffer from the strong hydrophobicity, deficient functionality, and insufficient compatibility with cell/organs. Consequently, the application is quite limited in scope. Due to the imparted appealing properties, aliphatic polycarbonates bearing specifically designed functional/reactive groups attract great interest from researchers in the recent years. The present review outlines the development up to date concerning the design and biomedical application of functional aliphatic polycarbonates, with an emphasis on their ring-opening (co)polymerization preparation. (C) 2011 Elsevier Ltd. All rights reserved.
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