Related references
Note: Only part of the references are listed.Apc Restoration Promotes Cellular Differentiation and Reestablishes Crypt Homeostasis in Colorectal Cancer
Lukas E. Dow et al.
CELL (2015)
Generating genetically modified mice using CRISPR/Cas-mediated genome engineering
Hui Yang et al.
NATURE PROTOCOLS (2014)
A Conditional System to Specifically Link Disruption of Protein-Coding Function with Reporter Expression in Mice
Shin-Heng Chiou et al.
CELL REPORTS (2014)
One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering
Hui Yang et al.
CELL (2013)
A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens
Jan H. Reiling et al.
NATURE CELL BIOLOGY (2013)
Conditionals by inversion provide a universal method for the generation of conditional alleles
Aris N. Economides et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Deciphering the Glycosylome of Dystroglycanopathies Using Haploid Screens for Lassa Virus Entry
Lucas T. Jae et al.
SCIENCE (2013)
Generation of primary tumors with Flp recombinase in FRT-flanked p53 mice
Chang-Lung Lee et al.
DISEASE MODELS & MECHANISMS (2012)
A pipeline for the generation of shRNA transgenic mice
Lukas E. Dow et al.
NATURE PROTOCOLS (2012)
Use and Abuse of RNAi to Study Mammalian Gene Function
William G. Kaelin
SCIENCE (2012)
MASTR: A Technique for Mosaic Mutant Analysis with Spatial and Temporal Control of Recombination Using Conditional Floxed Alleles in Mice
Zhimin Lao et al.
CELL REPORTS (2012)
A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference
Prem K. Premsrirut et al.
CELL (2011)
Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay
Christof Fellmann et al.
MOLECULAR CELL (2011)
Ebola virus entry requires the cholesterol transporter Niemann-Pick C1
Jan E. Carette et al.
NATURE (2011)
A haploid genetic screen identifies the major facilitator domain containing 2A (MFSD2A) transporter as a key mediator in the response to tunicamycin
Jan H. Reiling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Selective activation of p53-mediated tumour suppression in high-grade tumours
Melissa R. Junttila et al.
NATURE (2010)
Stage-specific sensitivity to p53 restoration during lung cancer progression
David M. Feldser et al.
NATURE (2010)
Tissue-specific p19(Arf) regulation dictates the response to oncogenic K-ras
Nathan P. Young et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase
Michel DuPage et al.
NATURE PROTOCOLS (2009)
Haploid Genetic Screens in Human Cells Identify Host Factors Used by Pathogens
Jan E. Carette et al.
SCIENCE (2009)
A system for Cre-regulated RNA interference in vivo
Patrick Stern et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
A spatially and temporally restricted mouse model of soft tissue sarcoma
David G. Kirsch et al.
NATURE MEDICINE (2007)
Tissue-specific and reversible RNA interference in transgenic mice
Ross A. Dickins et al.
NATURE GENETICS (2007)
Restoration of p53 function leads to tumour regression in vivo
Andrea Ventura et al.
NATURE (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
Modeling the therapeutic efficacy of p53 restoration in tumors
Carla P. Martins et al.
CELL (2006)
Minimizing the risk of reporting false positives in large-scale RNAi screens
Christophe J. Echeverri et al.
NATURE METHODS (2006)
Widespread siRNA off-target'' transcript silencing mediated by seed region sequence complementarity
Aimee L. Jackson et al.
RNA (2006)
Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors
Katerina Politi et al.
GENES & DEVELOPMENT (2006)
The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
Hongbin Ji et al.
CANCER CELL (2006)
Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
Dirk Grimm et al.
NATURE (2006)
The differential effects of mutant p53 alleles on advanced murine lung cancer
EL Jackson et al.
CANCER RESEARCH (2005)
Temporal dissection of p53 function in vitro and in vivo
MA Christophorou et al.
NATURE GENETICS (2005)
Genomewide production of multipurpose alleles for the functional analysis of the mouse genome
F Schnütgen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects
DA Tuveson et al.
CANCER CELL (2004)
A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse
F Schnütgen et al.
NATURE BIOTECHNOLOGY (2003)
An epi-allelic series of p53 hypomorphs created by stable RNAi produces distinct tumor phenotypes in vivo
MT Hemann et al.
NATURE GENETICS (2003)
Conditional activation of Neu in the mammary epithelium of transgenic mice results in reversible pulmonary metastasis
SE Moody et al.
CANCER CELL (2002)
Dissecting p53 tumor suppressor functions in vivo
CA Schmitt et al.
CANCER CELL (2002)
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
EL Jackson et al.
GENES & DEVELOPMENT (2001)
Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes
GH Fisher et al.
GENES & DEVELOPMENT (2001)
Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer
J Jonkers et al.
NATURE GENETICS (2001)
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
L Johnson et al.
NATURE (2001)
Cellular senescence: Mitotic clock or culture shock?
CJ Sherr et al.
CELL (2000)
Share Paper
