Journal
PROCESS BIOCHEMISTRY
Volume 47, Issue 11, Pages 1559-1562Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.procbio.2011.12.020
Keywords
Artemisia annua L.; Artemisinin; Chitosan oligosaccharide; Elicitor; Gene expression; Salicylic acid
Categories
Funding
- Danish Council for Strategic Research [FI.2101-08-0048]
- Sino-Danish Scientific and Technological Cooperation [08-039585]
- DANIDA (Denmark)
Ask authors/readers for more resources
Artemisia annua L. is a traditional Chinese medicinal plant used for treating fevers and malaria. The primary anti-malarial component is the sesquiterpene lactone peroxide artemisinin, which is accumulated in glandular trichomes. This study investigated the effect of treating plants with chitosan oligosaccharide (COS) and salicylic acid (SA) on both artemisinin production and gene expression related to the biosynthetic pathway of artemisinin. COS up-regulated the transcriptional levels of the genes ADS and TTG1 2.5 fold and 1.8 fold after 48 h individually, whereas SA only up-regulated ADS 2.0 fold after 48 h. LC-MS analysis showed that COS treatment increased artemisinin production in leaves slightly. These results suggest different responses of Artemisia annua to COS and SA treatment. The limited effects of COS and SA on artemisinin production reveal that elicitors may not be a universal method for increasing artemisinin yield or the up-regulation takes longer than 48 h to be effective. (C) 2011 Elsevier Ltd. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available