Related references
Note: Only part of the references are listed.Cryptic genetic variation promotes rapid evolutionary adaptation in an RNA enzyme
Eric J. Hayden et al.
NATURE (2011)
An integrated approach to characterize genetic interaction networks in yeast metabolism
Balazs Szappanos et al.
NATURE GENETICS (2011)
A systems analysis of mutational effects in HIV-1 protease and reverse transcriptase
Trevor Hinkley et al.
NATURE GENETICS (2011)
Negative Epistasis Between Beneficial Mutations in an Evolving Bacterial Population
Aisha I. Khan et al.
SCIENCE (2011)
Diminishing Returns Epistasis Among Beneficial Mutations Decelerates Adaptation
Hsin-Hung Chou et al.
SCIENCE (2011)
Molecular mechanisms of epistasis within and between genes
Ben Lehner
TRENDS IN GENETICS (2011)
Evolutionary Accessibility of Mutational Pathways
Jasper Franke et al.
PLOS COMPUTATIONAL BIOLOGY (2011)
Reciprocal Sign Epistasis between Frequently Experimentally Evolved Adaptive Mutations Causes a Rugged Fitness Landscape
Daniel J. Kvitek et al.
PLOS GENETICS (2011)
Epistasis between Beneficial Mutations and the Phenotype-to-Fitness Map for a ssDNA Virus
Darin R. Rokyta et al.
PLOS GENETICS (2011)
Initial Mutations Direct Alternative Pathways of Protein Evolution
Merijn L. M. Salverda et al.
PLOS GENETICS (2011)
Experimental evolution with E. coli in diverse resource environments. I. Fluctuating environments promote divergence of replicate populations
Tim F. Cooper et al.
BMC EVOLUTIONARY BIOLOGY (2010)
Fitness Epistasis and Constraints on Adaptation in a Human Immunodeficiency Virus Type 1 Protein Region
Jack da Silva et al.
GENETICS (2010)
Diminishing Returns From Beneficial Mutations and Pervasive Epistasis Shape the Fitness Landscape for Rifampicin Resistance in Pseudomonas aeruginosa
R. C. MacLean et al.
GENETICS (2010)
Fitness Epistasis among 6 Biosynthetic Loci in the Budding Yeast Saccharomyces cerevisiae
David W. Hall et al.
JOURNAL OF HEREDITY (2010)
Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks
Xionglei He et al.
NATURE GENETICS (2010)
Adaptive landscapes and protein evolution
Mauricio Carneiro et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
The Genetic Landscape of a Cell
Michael Costanzo et al.
SCIENCE (2010)
Environmental duress and epistasis: how does stress affect the strength of selection on new mutations?
Aneil F. Agrawal et al.
TRENDS IN ECOLOGY & EVOLUTION (2010)
Exploring the Effect of Sex on Empirical Fitness Landscapes
J. Arjan G. M. de Visser et al.
AMERICAN NATURALIST (2009)
Effects of Recombination on Complex Regulatory Circuits
Olivier C. Martin et al.
GENETICS (2009)
The Evolution of Epistasis and Its Links With Genetic Robustness, Complexity and Drift in a Phenotypic Model of Adaptation
Pierre-Alexis Gros et al.
GENETICS (2009)
SYSTEMS MICROBIOLOGY - OPINION Drug interactions and the evolution of antibiotic resistance
Pamela J. Yeh et al.
NATURE REVIEWS MICROBIOLOGY (2009)
Positive Epistasis Drives the Acquisition of Multidrug Resistance
Sandra Trindade et al.
PLOS GENETICS (2009)
Interactions between stressful environment and gene deletions alleviate the expected average loss of fitness in yeast
Lukasz Jasnos et al.
GENETICS (2008)
Quantitative exploration of the catalytic landscape separating divergent plant sesquiterpene synthases
Paul E. O'Maille et al.
NATURE CHEMICAL BIOLOGY (2008)
Epistasis - the essential role of gene interactions in the structure and evolution of genetic systems
Patrick C. Phillips
NATURE REVIEWS GENETICS (2008)
Heterogeneous Adaptive Trajectories of Small Populations on Complex Fitness Landscapes
Daniel E. Rozen et al.
PLOS ONE (2008)
A Network Model for the Correlation between Epistasis and Genomic Complexity
Rafael Sanjuan et al.
PLOS ONE (2008)
On the evolution of epistasis III: The haploid case with mutation
Uri Liberman et al.
THEORETICAL POPULATION BIOLOGY (2008)
The road to modularity
Gunter P. Wagner et al.
NATURE REVIEWS GENETICS (2007)
Evolution can favor antagonistic epistasis
Michael M. Desai et al.
GENETICS (2007)
Epistasis between deleterious mutations and the evolution of recombination
Roger D. Kouyos et al.
TRENDS IN ECOLOGY & EVOLUTION (2007)
A genome-scale metabolic reconstruction for Escherichia coli K-12 MG1655 that accounts for 1260 ORFs and thermodynamic information
Adam M. Feist et al.
MOLECULAR SYSTEMS BIOLOGY (2007)
A negative relationship between mutation pleiotropy and fitness effect in yeast
Tim F. Cooper et al.
EVOLUTION (2007)
Epistatic buffering of fitness loss in yeast double deletion strains
Lukasz Jasnos et al.
NATURE GENETICS (2007)
Mitotic recombination accelerates adaptation in the fungus Aspergillus nidulans
Sijmen E. Schoustra et al.
PLOS GENETICS (2007)
Distributions of epistasis in microbes fit predictions from a fitness landscape model
Guillaume Martin et al.
NATURE GENETICS (2007)
On the evolution of epistasis II: A generalized Wright-Kimura framework
Uri Liberman et al.
THEORETICAL POPULATION BIOLOGY (2007)
The evolution of sex: empirical insights into the roles of epistasis and drift
J. Arjan G. M. de Visser et al.
NATURE REVIEWS GENETICS (2007)
Experimental Rugged Fitness Landscape in Protein Sequence Space
Yuuki Hayashi et al.
PLOS ONE (2006)
Epistasis correlates to genomic complexity
Rafael Sanjuan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Darwinian evolution can follow only very few mutational paths to fitter proteins
DM Weinreich et al.
SCIENCE (2006)
Sexual reproduction selects for robustness and negative epistasis in artificial gene networks
RBR Azevedo et al.
NATURE (2006)
Sexual reproduction reshapes the genetic architecture of digital organisms
D Misevic et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2006)
Genomic buffering mitigates the effects of deleterious mutations in bacteria
S Maisnier-Patin et al.
NATURE GENETICS (2005)
The biochemical architecture of an ancient adaptive landscape
M Lunzer et al.
SCIENCE (2005)
Spontaneous evolution of modularity and network motifs
N Kashtan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The rate of compensatory mutation in the DNA bacteriophage φX174
A Poon et al.
GENETICS (2005)
Traversing the conceptual divide between biological and statistical epistasis: Systems biology and a more modern synthesis
JH Moore et al.
BIOESSAYS (2005)
On the evolution of epistasis I: diploids under selection
U Liberman et al.
THEORETICAL POPULATION BIOLOGY (2005)
The number of mutations selected during adaptation in a laboratory population of Saccharomyces cerevisiae
C Zeyl
GENETICS (2005)
Missense meanderings in sequence space: A biophysical view of protein evolution
MA DePristo et al.
NATURE REVIEWS GENETICS (2005)
Tumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
A Nebbioso et al.
NATURE MEDICINE (2005)
Pervasive joint influence of epistasis and plasticity on mutational effects in Escherichia coli
SK Remold et al.
NATURE GENETICS (2004)
Evidence for positive epistasis in HIV-1
S Bonhoeffer et al.
SCIENCE (2004)
The contribution of epistasis to the architecture of fitness in an RNA virus
R Sanjuán et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
RC MacLean et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
The effects of parasitism and inbreeding on the competitive ability in Daphnia magna:: evidence for synergistic epistasis
P Salathé et al.
JOURNAL OF EVOLUTIONARY BIOLOGY (2003)
Perspective: Evolution and detection of genetic robustness
JAGM de Visser et al.
EVOLUTION (2003)
Long-term experimental evolution in Escherichia coli. XI. Rejection of non-transitive interactions as cause of declining rate of adaptation
J. Arjan G. M. de Visser et al.
BMC EVOLUTIONARY BIOLOGY (2002)
Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs
XJ Wang et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Multidimensional epistasis and the disadvantage of sex
FA Kondrashov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Interaction between directional epistasis and average mutational effects
CO Wilke et al.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2001)
Evolution of digital organisms at high mutation rates leads to survival of the flattest
CO Wilke et al.
NATURE (2001)
Effects of environment on compensatory mutations to ameliorate costs of antibiotic resistance
J Björkman et al.
SCIENCE (2000)