Related references
Note: Only part of the references are listed.TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling
Yichuan Xiao et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Phylogenetic Analysis of Dysbiosis in Ulcerative Colitis During Remission
Mirjana Rajilic-Stojanovic et al.
INFLAMMATORY BOWEL DISEASES (2013)
The need for littermate controls
Rikard Holmdahl et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Mesenchymal Stem Cells and Prostaglandins May Be Critical for Intestinal Wound Repair
Don W. Powell et al.
GASTROENTEROLOGY (2012)
Igf2bp1 Is Required for Full Induction of Ptgs2 mRNA in Colonic Mesenchymal Stem Cells in Mice
Nicholas A. Manieri et al.
GASTROENTEROLOGY (2012)
IκB kinase regulation of the TPL-2/ERK MAPK pathway
Thorsten Gantke et al.
IMMUNOLOGICAL REVIEWS (2012)
Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis
Vasiliki Koliaraki et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Familial transmission rather than defective innate immunity shapes the distinct intestinal microbiota of TLR-deficient mice
Carles Ubeda et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Genetic and pharmacological targeting of TPL-2 kinase ameliorates experimental colitis: a potential target for the treatment of Crohn's disease
M. Lawrenz et al.
MUCOSAL IMMUNOLOGY (2012)
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
Luke Jostins et al.
NATURE (2012)
Tpl2 ablation promotes intestinal inflammation and tumorigenesis in Apcmin mice by inhibiting IL-10 secretion and regulatory T-cell generation
Oksana B. Serebrennikova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Mesenchymal Cells of the Intestinal Lamina Propria
D. W. Powell et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 73 (2011)
Cox-2 deletion in myeloid and endothelial cells, but not in epithelial cells, exacerbates murine colitis.
Tomo-o Ishikawa et al.
CARCINOGENESIS (2011)
NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis
Eran Elinav et al.
CELL (2011)
Twin Study Indicates Loss of Interaction Between Microbiota and Mucosa of Patients With Ulcerative Colitis
Patricia Lepage et al.
GASTROENTEROLOGY (2011)
Genome-Wide Expression Profiling Identifies an Impairment of Negative Feedback Signals in the Crohn's Disease-Associated NOD2 Variant L1007fsinsC
Susanne Billmann-Born et al.
JOURNAL OF IMMUNOLOGY (2011)
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
Kenichiro Furuyama et al.
NATURE GENETICS (2011)
Isolation and in vitro expansion of human colonic stem cells
Peter Jung et al.
NATURE MEDICINE (2011)
Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology
Manolis Roulis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury
Sylvain Normand et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Inflammatory Bowel Disease
Arthur Kaser et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 28 (2010)
The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
Md. Hasan Zaki et al.
IMMUNITY (2010)
Effect of EP4 Agonist (ONO-4819CD) for Patients with Mild to Moderate Ulcerative Colitis Refractory to 5-Aminosalicylates: a Randomized Phase II, Placebo-Controlled Trial
Hiroshi Nakase et al.
INFLAMMATORY BOWEL DISEASES (2010)
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
Katharina Brandl et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Intestinal stem cells and epithelial-mesenchymal interactions in the crypt and stem cell niche
Anisa Shaker et al.
TRANSLATIONAL RESEARCH (2010)
Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration
Wolfram Goessling et al.
CELL (2009)
Targeting protein kinases for the development of anti-inflammatory drugs
Philip Cohen
CURRENT OPINION IN CELL BIOLOGY (2009)
Tumor Progression Locus 2 (Map3k8) Is Critical for Host Defense against Listeria monocytogenes and IL-1β Production
Lisa A. Mielke et al.
JOURNAL OF IMMUNOLOGY (2009)
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche
Akifumi Ootani et al.
NATURE MEDICINE (2009)
Tpl2 kinase regulates T cell interferon-γ production and host resistance to Toxoplasma gondii
Wendy T. Watford et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases
Maria Armaka et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
Harry Sokol et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
Pauline Bastide et al.
JOURNAL OF CELL BIOLOGY (2007)
Epithelial NEMO links innate immunity to chronic intestinal inflammation
Arianna Nenci et al.
NATURE (2007)
Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury
Sarah L. Brown et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine
Masayuki Fukata et al.
GASTROENTEROLOGY (2006)
Conditional knockout mouse for tissue-specific disruption of the cyclooxygenase-2 (Cox-2) gene
T Ishikawa et al.
GENESIS (2006)
NAD(+)-linked 15-hydroxyprostaglandin dehydrogenase: Structure and biological functions
HH Tai et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Epithelial cells and their neighbors I. Role of intestinal myofibroblasts in development, repair, and cancer
DW Powell et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Tpl2/Cot signals activate ERK, JNK, and NF-κB in a cell-type and stimulus-specific manner
S Das et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis
M Fukata et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
S Rakoff-Nahoum et al.
CELL (2004)
Tpl2 transduces CD40 and TNF signals that activate ERK and regulates IgE induction by CD40
AG Eliopoulos et al.
EMBO JOURNAL (2003)
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease
D Kontoyiannis et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Induction of COX-2 by LPS in macrophages is regulated by Tpl2-dependent CREB activation signals
AG Eliopoulos et al.
EMBO JOURNAL (2002)
cis elements of the villin gene control expression in restricted domains of the vertical (crypt) and horizontal (duodenum, cecum) axes of the intestine
BB Madison et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
TNF-α induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway
CD Dumitru et al.
CELL (2000)
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2
O Morteau et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)