4.8 Article

Ultrasensitive detection of waste products in water using fluorescence emission cavity-enhanced spectroscopy

Publisher

NATL ACAD SCIENCES
DOI: 10.1073/pnas.1403175111

Keywords

water contamination; fluorescence spectroscopy; femtomolar detection

Funding

  1. National Science Foundation [ECCS-1250360, DBI-1250361, CBET-125063, PHY-1241032, EEC-0540832]
  2. Robert A. Welch Foundation [A-1261]
  3. Herman F. Heep and Minnie Belle Heep Texas A&M University Endowed Fund
  4. Direct For Mathematical & Physical Scien
  5. Division Of Physics [1241032] Funding Source: National Science Foundation
  6. Directorate For Engineering
  7. Div Of Chem, Bioeng, Env, & Transp Sys [1250363] Funding Source: National Science Foundation
  8. Directorate For Engineering
  9. Div Of Electrical, Commun & Cyber Sys [1250360] Funding Source: National Science Foundation

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Clean water is paramount to human health. In this article, we present a technique for detection of trace amounts of human or animal waste products in water using fluorescence emission cavity-enhanced spectroscopy. The detection of femtomolar concentrations of urobilin, a metabolic byproduct of heme metabolism that is excreted in both human and animal waste in water, was achieved through the use of an integrating cavity. This technique could allow for real-time assessment of water quality without the need for expensive laboratory equipment.

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