Related references
Note: Only part of the references are listed.The discovery of potent blockers of the canonical transient receptor channels, TRPC3 and TRPC6, based on an anilino-thiazole pharmacophore
David G. Washburn et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca2+ entry pathways
H. Schleifer et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Novel pharmacological TRPC inhibitors block hypoxia-induced vasoconstriction
Nicole Urban et al.
CELL CALCIUM (2012)
A TRPC6-Dependent Pathway for Myofibroblast Transdifferentiation and Wound Healing In Vivo
Jennifer Davis et al.
DEVELOPMENTAL CELL (2012)
Ca2+ influx through L-type Ca2+ channels and transient receptor potential channels activates pathological hypertrophy signaling
Hui Gao et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Store-operated calcium entry is present in HL-1 cardiomyocytes and contributes to resting calcium
Chad D. Touchberry et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2011)
TRPC Channels As Effectors of Cardiac Hypertrophy
Petra Eder et al.
CIRCULATION RESEARCH (2011)
Pharmacological Modulation of Diacylglycerol-Sensitive TRPC3/6/7 Channels
Christian Harteneck et al.
CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2011)
Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+-Dependent Toxicity
Min Seuk Kim et al.
GASTROENTEROLOGY (2011)
Reactive Oxygen Species-mediated TRPC6 Protein Activation in Vascular Myocytes, a Mechanism for Vasoconstrictor-regulated Vascular Tone
Yanfeng Ding et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2
Michael Klaiber et al.
BASIC RESEARCH IN CARDIOLOGY (2010)
The transient receptor potential channel antagonist SKF96365 is a potent blocker of low-voltage-activated T-type calcium channels
A. Singh et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart
Hideyuki Kinoshita et al.
CIRCULATION RESEARCH (2010)
Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation Novel mechanism of cardiac stress modulation by PDE5 inhibition
Norimichi Koitabashi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
Canonical TRP channels and mechanotransduction: from physiology to disease states
Amanda Patel et al.
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY (2010)
TRPC channels are necessary mediators of pathologic cardiac hypertrophy
Xu Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Inhibition of TRPC1/TRPC3 by PKG contributes to NO-mediated vasorelaxation
Jie Chen et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2009)
Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound
Shigeki Kiyonaka et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
TRPC3 channels are required for synaptic transmission and motor coordination
Jana Hartmann et al.
NEURON (2008)
Upregulation of TRPC1 in the development of cardiac hypertrophy
Takayoshi Ohba et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Integration of phosphoinositide- and calmodulin-mediated regulation of TRPC6
Young Kwon et al.
MOLECULAR CELL (2007)
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
Koichiro Kuwahara et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
TRPC3 and TRPC6 are essential for angiotensin II-induced cardiac hypertrophy
Naoya Onohara et al.
EMBO JOURNAL (2006)
A common mechanism underlies stretch activation and receptor activation of TRPC6 channels
Maria A. Spassova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Identification of two domains involved in the assembly of transient receptor potential canonical channels
Pascale K. Lepage et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Calcineurin-dependent cardiomyopathy is activated by TRPC in the adult mouse heart
Hiroyuki Nakayama et al.
FASEB JOURNAL (2006)
Increased vascular smooth muscle contractility in TRPC6-/- mice
A Dietrich et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Carvedilol effectively blocks oxidative stress-mediated downregulation of sarcoplasmic reticulum Ca2+-ATPase 2 gene transcription through modification of Sp1 binding
N Koitabashi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
E Takimoto et al.
NATURE MEDICINE (2005)
Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2
C Zitt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy
BJ Wilkins et al.
CIRCULATION RESEARCH (2004)
FRET-based analysis of TRPC subunit stoichiometry
H Amiri et al.
CELL CALCIUM (2003)
Independent signals control expression of the calcineurin inhibitory proteins MCIP1 and MCIP2 in striated muscles
J Yang et al.
CIRCULATION RESEARCH (2000)
Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels
TM Suchyna et al.
JOURNAL OF GENERAL PHYSIOLOGY (2000)