Related references
Note: Only part of the references are listed.The Intrinsic Apoptosis Pathway Mediates the Pro-Longevity Response to Mitochondrial ROS in C. elegans
Callista Yee et al.
CELL (2014)
DAF-16/FoxO Directly Regulates an Atypical AMP-Activated Protein Kinase Gamma Isoform to Mediate the Effects of Insulin/IGF-1 Signaling on Aging in Caenorhabditis elegans
Jennifer M. A. Tullet et al.
PLOS GENETICS (2014)
CEP-1, the Caenorhabditis elegans p53 Homolog, Mediates Opposing Longevity Outcomes in Mitochondrial Electron Transport Chain Mutants
Aiswarya Baruah et al.
PLOS GENETICS (2014)
TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species
Francisco J. Roca et al.
CELL (2013)
Muscle Mitohormesis Promotes Longevity via Systemic Repression of Insulin Signaling
Edward Owusu-Ansah et al.
CELL (2013)
Epigenetic Silencing Mediates Mitochondria Stress-Induced Longevity
Elizabeth A. Schroeder et al.
CELL METABOLISM (2013)
The complex interplay of iron metabolism, reactive oxygen species, and reactive nitrogen species: Insights into the potential of various iron therapies to induce oxidative and nitrosative stress
Taija S. Koskenkorva-Frank et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Mitonuclear protein imbalance as a conserved longevity mechanism
Riekelt H. Houtkooper et al.
NATURE (2013)
Genome-Wide Microarrray Analysis Reveals Roles for the REF-1 Family Member HLH-29 in Ferritin Synthesis and Peroxide Stress Response
Thanh K. Quach et al.
PLOS ONE (2013)
Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis
Guoxiang Yuan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Increased Levels of Hydrogen Peroxide Induce a HIF-1-dependent Modification of Lipid Metabolism in AMPK Compromised C. elegans Dauer Larvae
Meng Xie et al.
CELL METABOLISM (2012)
Divalent Metal Transporter 1 Regulates Iron-Mediated ROS and Pancreatic β Cell Fate in Response to Cytokines
Jakob Bondo Hansen et al.
CELL METABOLISM (2012)
Mitochondria and Organismal Longevity
Ara B. Hwang et al.
CURRENT GENOMICS (2012)
Immune defense mechanisms in the Caenorhabditis elegans intestinal epithelium
Read Pukkila-Worley et al.
CURRENT OPINION IN IMMUNOLOGY (2012)
Physiological Roles of Mitochondrial Reactive Oxygen Species
Laura A. Sena et al.
MOLECULAR CELL (2012)
AMPK: a nutrient and energy sensor that maintains energy homeostasis
D. Grahame Hardie et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
Superoxide dismutase is dispensable for normal animal lifespan
Jeremy Michael Van Raamsdonk et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Insulin/IGF-1 and Hypoxia Signaling Act in Concert to Regulate Iron Homeostasis in Caenorhabditis elegans
Daniel Ackerman et al.
PLOS GENETICS (2012)
An Engineering Approach to Extending Lifespan in C. elegans
Dror Sagi et al.
PLOS GENETICS (2012)
HIF-1 modulates longevity and healthspan in a temperature-dependent manner
Scott F. Leiser et al.
AGING CELL (2011)
The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
Jenni Durieux et al.
CELL (2011)
Extending life span by increasing oxidative stress
Michael Ristow et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB
William Mair et al.
NATURE (2011)
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
A. Phillip West et al.
NATURE (2011)
OASIS: Online Application for the Survival Analysis of Lifespan Assays Performed in Aging Research
Jae-Seong Yang et al.
PLOS ONE (2011)
Taking a good look at free radicals in the aging process
Siegfried Hekimi et al.
TRENDS IN CELL BIOLOGY (2011)
The Homeobox Protein CEH-23 Mediates Prolonged Longevity in Response to Impaired Mitochondrial Electron Transport Chain in C. elegans
Ludivine Walter et al.
PLOS BIOLOGY (2011)
HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage
Steven Joshua Romney et al.
PLOS GENETICS (2011)
Inhibition of Respiration Extends C. elegans Life Span via Reactive Oxygen Species that Increase HIF-1 Activity
Seung-Jae Lee et al.
CURRENT BIOLOGY (2010)
HIF-1: upstream and downstream of cancer metabolism
Gregg L. Semenza
CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)
Elevated Mitochondrial Reactive Oxygen Species Generation Affects the Immune Response via Hypoxia-Inducible Factor-1α in Long-Lived Mclk1+/- Mouse Mutants
Dantong Wang et al.
JOURNAL OF IMMUNOLOGY (2010)
Energetics, epigenetics, mitochondrial genetics
Douglas C. Wallace et al.
MITOCHONDRION (2010)
Hydrogen Sulfide Increases Hypoxia-inducible Factor-1 Activity Independently of von Hippel-Lindau Tumor Suppressor-1 in C-elegans
Mark W. Budde et al.
MOLECULAR BIOLOGY OF THE CELL (2010)
Hypoxia signaling and resistance in C. elegans
Jo Anne Powell-Coffman
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2010)
Dual oxidase in mucosal immunity and host-microbe homeostasis
Yun Soo Bae et al.
TRENDS IN IMMUNOLOGY (2010)
A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans
Wen Yang et al.
PLOS BIOLOGY (2010)
C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1-Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1
Zhiyong Shao et al.
PLOS PATHOGENS (2010)
Intestinal Hypoxia-inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency
Yatrik M. Shah et al.
CELL METABOLISM (2009)
Extension of Drosophila Life Span by RNAi of the Mitochondrial Respiratory Chain
Jeffrey M. Copeland et al.
CURRENT BIOLOGY (2009)
Activation of the AMPK-FOXO3 Pathway Reduces Fatty Acid-Induced Increase in Intracellular Reactive Oxygen Species by Upregulating Thioredoxin
Xiao-Nan Li et al.
DIABETES (2009)
Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis
Kai Hartwig et al.
GENES AND NUTRITION (2009)
Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
Patrick Narbonne et al.
NATURE (2009)
The HIF-1 Hypoxia-Inducible Factor Modulates Lifespan in C. elegans
Yi Zhang et al.
PLOS ONE (2009)
Proteasomal Regulation of the Hypoxic Response Modulates Aging in C-elegans
Ranjana Mehta et al.
SCIENCE (2009)
HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans
Di Chen et al.
PLOS GENETICS (2009)
A Regulated Response to Impaired Respiration Slows Behavioral Rates and Increases Lifespan in Caenorhabditis elegans
David Cristina et al.
PLOS GENETICS (2009)
Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans
Audrey Bellier et al.
PLOS PATHOGENS (2009)
The LKB1-AMPK pathway: metabolism and growth control in tumour suppression
David B. Shackelford et al.
NATURE REVIEWS CANCER (2009)
Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes
Zhonglin Xie et al.
DIABETES (2008)
The Caenorhabditis elegans AMP-activated protein kinase AAK-2 is phosphorylated by LKB1 and is required for resistance to oxidative stress and for normal motility and foraging behavior
Hyojin Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Oxygen levels affect axon guidance and neuronal migration in Caenorhabditis elegans
Roger Pocock et al.
NATURE NEUROSCIENCE (2008)
Hypoxia, HIF1 and glucose metabolism in the solid tumour
Nicholas C. Denko
NATURE REVIEWS CANCER (2008)
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C-elegans
Eric L. Greer et al.
CURRENT BIOLOGY (2007)
Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress
Tim J. Schulz et al.
CELL METABOLISM (2007)
Oxidative stress enzymes are required for DAF-16-mediated immunity due to generation of reactive oxygen species by Caenorhabditis elegans
Violeta Chavez et al.
GENETICS (2007)
Increased longevity and refractoriness to Ca2+-dependent neurodegeneration in Surf1 knockout mice
Carlotta Dell'Agnello et al.
HUMAN MOLECULAR GENETICS (2007)
Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection
Daniel Wong et al.
GENOME BIOLOGY (2007)
p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
Emily R. Troemel et al.
PLOS GENETICS (2006)
A conserved role for a GATA transcription factor in regulating epithelial innate immune responses
Michael Shapira et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum
Delia O'Rourke et al.
GENOME RESEARCH (2006)
Aging networks in Caenorhabditis elegans:: AMP-activated protein kinase (aak-2) links multiple aging and metabolism pathways
R Curtis et al.
AGING CELL (2006)
Evolutionary conservation of the clk-1-dependent mechanism of longevity:: loss of mclk1 increases cellular fitness and lifespan in mice
XX Liu et al.
GENES & DEVELOPMENT (2005)
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones
T Yoneda et al.
JOURNAL OF CELL SCIENCE (2004)
The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C-elegans
J Apfeld et al.
GENES & DEVELOPMENT (2004)
Long-lived C-elegans daf-2 mutants are resistant to bacterial pathogens
DA Garsin et al.
SCIENCE (2003)
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
JL Feng et al.
DEVELOPMENTAL CELL (2001)
A gene expression map for Caenorhabditis elegans
SK Kim et al.
SCIENCE (2001)
A simple model host for identifying Gram-positive virulence factors
DA Garsin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia
HQ Jiang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
D Arsenijevic et al.
NATURE GENETICS (2000)
Share Paper
