Related references
Note: Only part of the references are listed.TRIAD1 and HHARI bind to and are activated by distinct neddylated Cullin-RING ligase complexes
Ian R. Kelsall et al.
EMBO JOURNAL (2013)
Advances in the clinical development of heat shock protein 90 (Hsp90) inhibitors in cancers
Komal Jhaveri et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2012)
Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition
Mikko Taipale et al.
CELL (2012)
Hsp90 Molecular Chaperone Inhibitors: Are We There Yet?
Len Neckers et al.
CLINICAL CANCER RESEARCH (2012)
Structural assembly of cullin-RING ubiquitin ligase complexes
Erik S. Zimmerman et al.
CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)
BIIB021, an orally available, fully synthetic small-molecule inhibitor of the heat shock protein Hsp90
Karen Lundgren et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Silencing the cochaperone CDC37 destabilizes kinase clients and sensitizes cancer cells to HSP90 inhibitors
J. R. Smith et al.
ONCOGENE (2009)
Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase
Elana S. Ehrlich et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and increases cellular sensitivity to the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin
Joanna L. Holmes et al.
CANCER RESEARCH (2008)
NVP-AUY922: A novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis
Suzanne A. Eccles et al.
CANCER RESEARCH (2008)
4,5-diarylisoxazole HSP90 chaperone inhibitors: Potential therapeutic agents for the treatment of cancer
Paul A. Brough et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors
OM Grbovic et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Geldanamycin stimulates internalization of ErbB2 in a proteasome-dependent way
M Lerdrup et al.
JOURNAL OF CELL SCIENCE (2006)
Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin
SD Dias et al.
CANCER RESEARCH (2005)
Function and regulation of Cullin-RING ubiquitin ligases
MD Petroski et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Nedd8 on cullin: building an expressway to protein destruction
ZQ Pan et al.
ONCOGENE (2004)
T47D breast cancer cell growth is inhibited by expression of VACM-1, a cul-5 gene
MA Burnatowska-Hledin et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2004)
Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex
XH Yu et al.
SCIENCE (2003)
VACM-1, a cul-5 gene, inhibits cellular growth by a mechanism that involves MAPK and p53 signaling pathways
C Van Dort et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2003)
The protein kinase complement of the human genome
G Manning et al.
SCIENCE (2002)
Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2 Neu
WP Xu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Ansamycin antibiotics inhibit Akt activation and cyclin D expression in breast cancer cells that overexpress HER2
AD Basso et al.
ONCOGENE (2002)
HSP90 as a new therapeutic target for cancer therapy: the story unfolds
A Maloney et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2002)
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
P Connell et al.
NATURE CELL BIOLOGY (2001)
Geldanamycin induces ErbB-2 degradation by proteolytic fragmentation
O Tikhomirov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
