4.8 Article

Membrane lipid saturation activates endoplasmic reticulum unfolded protein response transducers through their transmembrane domains

Related references

Note: Only part of the references are listed.
Article Biochemical Research Methods

The structure of the PERK kinase domain suggests the mechanism for its activation

Wenjun Cui et al.

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2011)

Article Biochemistry & Molecular Biology

Molecular Mechanism by Which Palmitate Inhibits PKR Autophosphorylation

Hyunju Cho et al.

BIOCHEMISTRY (2011)

Article Multidisciplinary Sciences

The mechanism of membrane-associated steps in tail-anchored protein insertion

Malaiyalam Mariappan et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

The membrane environment modulates self-association of the human GpA TM domain-Implications for membrane protein folding and transmembrane signaling

Veerappan Anbazhagan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2010)

Article Chemistry, Medicinal

Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438)

Serge Leger et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2010)

Article Biochemistry & Molecular Biology

Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response

Hiroyuki Ariyama et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Review Cell Biology

Regulation of basal cellular physiology by the homeostatic unfolded protein response

D. Thomas Rutkowski et al.

JOURNAL OF CELL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Flavonol Activation Defines an Unanticipated Ligand-Binding Site in the Kinase-RNase Domain of IRE1

R. Luke Wiseman et al.

MOLECULAR CELL (2010)

Article Biochemistry & Molecular Biology

BiP Binding to the ER-Stress Sensor Ire1 Tunes the Homeostatic Behavior of the Unfolded Protein Response

David Pincus et al.

PLOS BIOLOGY (2010)

Article Chemistry, Medicinal

Novel, potent, selective, and metabolically stable stearoyl-CoA desaturase (SCD) inhibitors

Dmitry O. Koltun et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2009)

Article Endocrinology & Metabolism

Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

Margaret F. Gregor et al.

DIABETES (2009)

Article Biochemistry & Molecular Biology

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

Chih-Chi Andrew Hu et al.

EMBO JOURNAL (2009)

Review Cell Biology

Initiation and execution of lipotoxic ER stress in pancreatic β-cells

Daniel A. Cunha et al.

JOURNAL OF CELL SCIENCE (2008)

Review Cell Biology

Membrane lipids: where they are and how they behave

Gerrit van Meer et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

Conserved intermolecular salt bridge required for activation of protein kinases PKR, GCN2, and PERK

Madhusudan Dey et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

Nica M. Borradaile et al.

JOURNAL OF LIPID RESEARCH (2006)

Article Multidisciplinary Sciences

The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response

Jiahai Zhou et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Multidisciplinary Sciences

On the mechanism of sensing unfolded protein in the endoplasmic reticulum

JJ Credle et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)

Article Biochemistry & Molecular Biology

Cytoprotection by pre-emptive conditional phosphorylation of translation initiation factor 2

PD Lu et al.

EMBO JOURNAL (2004)

Article Biochemistry & Molecular Biology

Activation of an unfolded protein response during differentiation of antibody-secreting B cells

JN Gass et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Dissociation of Kar2p/BiP from an ER sensory molecule, Ire1p, triggers the unfolded protein response in yeast

K Okamura et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)